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A massive snowstorm that has already turned deadly churned up the East Coast on Friday, forecast to transform into an angry blizzard that could bury the nation's capital under more than 2 feet of snow. 

The weekend whiteout has led to more than 6,000 canceled flights and caused at least 10 deaths.

The sprawling storm will blast snow across 15 states beginning Friday afternoon and evening and continuing well into Sunday, forecasters say. That has prompted rare blizzard warnings not only for Washington, D.C., but also Baltimore, New York City, Philadelphia, Trenton, New Jersey, and Long Island, New York. 

Live Updates: Millions Brace for Major Snowstorm

"We see this as a major storm. It has life and death implications. And all the residents of the District of Columbia should treat it that way," Washington, D.C., Mayor Muriel Bowser said.

The main priority, Bowser said, was to keep people safe, from students to commuters to the homeless. Public schools were closed Friday, the Metro will stop operating at 11 p.m. and outreach workers will try to find shelter for people who would otherwise sleep outside. 

Federal government workers were told to leave work at noon Friday ahead of the front edge of the blizzard.